Oxford said it would probably be alright, Pfizer warned against it.
tbh, it's... risky going against the medical tests; in effect you make us the live trial, which is... fraught with danger. Now it looks like it might well come off, which is great, but it's still risky. Was nervous at the time with it and the only reason I wouldn't go on the offensive then, or now for that matter, is because it did seem, at least, to be led by the medical advice (you know, Mr negative Whitty
)
As for variants, wouldn't it be nice if what we ended up with next was a nice weak, easily transmissable variant. Go on Covid, you know you want to!